产品货号：
Z28233
中文名称：
TIGAR抗体
英文名称：
Anti-TIGAR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TIGAR Antibody |
| 指标别名 | C12orf5,TIGAR |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | TIGAR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TIGAR antibody was raised against a 18 amino acid synthetic peptide from near the center of human TIGAR.The immunogen is located within amino acids 60 - 110 of TIGAR. |
| 计算分子量 | 30kDa |
| 成分 | TIGAR Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TIGAR Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p53 tumor-suppressor gene integrates numerous signals that control cell life and death;loss of its functions contributes to the development of most cancers.Recent studies have demonstrated the ability of p53 to regulate the expression of several proteins involved in glycolysis and oxidative phosphorylation,such as TIGAR,SCO2,and phosphoglycerate mutase.TIGAR is a recently discovered protein that functions to regulate glycolysis and protect cells against oxidative stress.TIGAR is similar in structure to proteins in the phosphoglycerate mutase family,most notably 6-phosphofructo-2-kinase,suggesting TIGAR may function as a fructose bisphosphatase.Expression of TIGAR in transfected cells correlated with an inhibition of glycolysis and decreased levels of reactive oxygen species and p53-induced apoptosis,indicating that TIGAR may act to modulate the apoptotic response to p53,thereby allowing cells to survive mild or transient stresses. |
| Uniprot ID | Q9NQ88 |
| 基因名全称 | Chromosome 12 open reading frame 5 |
| 蛋白名全称 | Chromosome 12 open reading frame 5 |
| 推荐稀释比 | TIGAR antibody can be used for detection of TIGAR by Western blot at 0.5 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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